There are three or four years of enlarged lymph nodes in the neck need to clarify the specific lymphoma, cancer or other causes, according to the situation using surgery, radiotherapy, chemotherapy, etc. to treat. 1. Lymphoma: Lymphoma can invade the lymph nodes in the neck, resulting in painless enlargement. Usually, pathologic puncture examination is done to clarify the pathologic typing, and after diagnosis, radiotherapy or chemotherapy is carried out, such as ABVD chemotherapy regimen, which consists of adriamycin, bleomycin, vincristine and dacarbazine, and bone marrow transplantation and other treatments can also be considered. 2. Cancer: A variety of malignant tumors can metastasize to the lymph nodes in the neck leading to enlargement, such as breast cancer, lung cancer, thyroid cancer, gastric cancer and many other cancers. It is necessary to do puncture pathologic examination to clarify whether it is metastatic cancer and its source. After diagnosis, surgical resection with lymph node dissection is usually adopted, and radiotherapy can be given after surgery. 3. Other conditions: chronic inflammation can lead to swelling of cervical lymph nodes for many years, which can be treated with long-term oral amoxicillin, cefixime and other antibiotics, and the lumps will be gradually reduced after the inflammation is eliminated. Tuberculous cervical lymphadenitis needs to be treated with anti-tuberculosis drugs such as isoniazid and rifampicin. To summarize, for long-term neck lumps should pay attention to, as soon as possible to the hospital examination, clear the nature of the lumps, to avoid the development of the disease, the above drugs must be used under the guidance of specialists, do not blindly use their own medication.