IgA nephropathy renal function creatinine 150μmol/L, should be clear about the cause of creatinine elevation. If it is due to blood volume insufficiency, it needs to replenish fluids in time; if it is due to IgA nephropathy itself, it usually needs high-dose hormone or combined cyclophosphamide shock therapy; if it is a chronic lesion, you can take creatinine-lowering medicines such as nephronin and urotoxin. IgA nephropathy creatinine 150μmol/L, if it is caused by blood volume insufficiency, infection, post renal obstruction, etc., it can be treated with rehydration, correction of renal perfusion, anti-infection, relief of obstruction, etc., and generally can be restored to normal. If it is caused by IgA nephropathy itself, considering the current pathological type is more serious, high-dose hormone or combined cyclophosphamide shock treatment can be carried out, and attention can be paid to prevent infection during treatment, and immunoglobulin can be supplemented if necessary. IgA nephropathy creatinine 150 μmol / L, if chronic lesions, this stage in addition to taking Haikun Kidney Xi, urethane clear granules and other proprietary medicines for treatment. It is also necessary to control the patient’s proteinuria and hypertension. Clinical application of renin-angiotensin-aldosterone receptor antagonist antihypertensive drugs (captopril tablets, irbesartan tablets, etc.) is often used to lower blood pressure and lower urinary protein at the same time, delaying the progression of kidney disease. In addition, patients should control the diet, patients should be low-salt, low-fat, low quality protein diet, careful use of nephrotoxic drugs, so as not to aggravate the burden on the kidneys, aggravate the progression of kidney disease. The above medication should follow the doctor’s prescription, not unauthorized use of drugs, so as not to aggravate the condition. It is recommended that patients with IgA nephropathy with elevated creatinine should consult regular hospitals in time to clarify the cause of the disease and carry out targeted treatment.