High basal metabolic rate is usually called negative nitrogen balance, which means that the three major nutrient metabolites such as protein, fat and sugar intake in the body cannot meet the demand of consumption, that is, the amount of sugar, protein and fat required for consumption far exceeds the amount of intake, so the body will appear thin, weak, malnutrition, absorption disorders, anemia and so on. Common diseases with high basal metabolic rate include endocrine diseases, usually diabetes, hyperthyroidism, hyperadrenalism and other diseases, especially the thyroid-adrenal-gonadal axis disorder around menopause and puberty in women is a significant clinical cause, common tumors, tuberculosis and other wasting diseases will also have high basal metabolic rate.