Lymph node enlargement is related to disease stimulation, and whether it can be self-healed mainly depends on the triggering cause. If it is caused by inflammation and immune factors, part of it can be cured by itself; if it is caused by tumor or tuberculosis, it basically cannot be cured by itself. 1. Inflammatory stimulation and immune factors: it will lead to reactive hyperplasia and enlargement of lymph nodes, part of the population, with the inflammation subsiding and immune system diseases gradually stabilizing, the lymph nodes can shrink by themselves and gradually heal by themselves, which is closely related to the physical condition, but most of them need to be controlled by medication. 2. Caused by tuberculosis or tumor lesions: the enlarged lymph nodes cannot shrink by themselves and need to be treated with appropriate medication or surgery before they can be cured. If you have obvious enlarged lymph nodes that cannot be relieved, you need to consult a doctor in time, complete the examination, make a clear diagnosis, and then standardize the treatment under the guidance of the clinician.