Hypoproteinemia is generally not life-threatening if treatment is administered in a timely manner. When the albumin level is below 20g/L, the mortality rate is about 54%, but the specific life cycle for how long is related to a variety of factors such as the degree of the original disease, the patient’s physical condition and the underlying disease, and varies widely among individuals. Hypoproteinemia is generally diagnosed in normal individuals with total serum protein below 60g/L or albumin below 35g/L. There are many causes of hypoproteinemia, commonly: 1, insufficient protein intake or malabsorption, such as serious heart, lung, liver, kidney disorders, gastrointestinal stasis, brain lesions; 2, protein synthesis disorders, such as various causes of liver damage, so that the liver protein synthesis capacity is reduced; 3, long-term massive protein loss, such as peptic ulcers, nephrotic syndrome, diabetic nephropathy, large trauma ooze; 4 , accelerated protein catabolism, such as long-term fever, malignant tumor, hyperthyroidism, etc. These are the predisposing causes of hypoproteinemia, and the primary diseases need to be treated simultaneously. Hypoproteinemia can be corrected by infusion of human albumin supplemented with dietary therapy, and by eating more lean meat, soybeans and other high quality protein foods if the condition allows. The treatment should be accompanied by dynamic monitoring of plasma albumin changes and liver and kidney function in order to adjust the treatment plan at any time.