Feeling testicular soreness may be caused by diseases such as syringomyelia, varicocele, epididymitis and so on. 1. Syringomyelia: the occurrence of this disease is related to the chronic inflammation of syringomyelia, syphilis, tumor, filariasis and scrotal surgery, hernia surgery and other reasons. Generally, when the fluid is small, the patient has no conscious symptoms, when the fluid is too much, the patient’s testicles will have a falling sensation, tugging pain, cyst enlargement and other symptoms, and in some cases, the patient will feel testicular acid. 2. Varicocele: the etiology of this disease is not clear, it may be related to venous valve underdevelopment or incomplete closure, venous return obstacles, including hydronephrosis, Nutcracker syndrome and so on. Severe symptoms will appear scrotum enlargement, accompanied by swelling, hidden pain and other symptoms, which can be manifested as feeling testicular acid. 3. Epididymitis: This disease is mainly caused by bacterial infection, such as Escherichia coli, Staphylococcus aureus and so on. In case of gonococcal or Chlamydia trachomatis infections, the infection can be transmitted sexually. It is also associated with congenital obstruction of the vas deferens and urinary reflux causes. Typical symptoms are scrotal swelling, erythema, pain, etc. Some patients may feel testicular soreness. It is recommended that patients who feel testicular acidity go to the hospital to improve the relevant examination to clarify the specific cause.