Unilateral sore throat, painful swallowing may be due to tonsillitis, pharyngitis or trauma and other factors. 1. Tonsillitis: acute attack of tonsillitis due to tonsil congestion and swelling, local inflammatory reaction leading to pain, there may be a side of the tonsil abscess, the pain is more intense, when swallowing the tonsils are squeezed easy to appear unilateral pain. 2. Pharyngitis: inflammation is confined to one side of the throat, one side of the mucous membrane appears red, swollen, hot and painful, there may be unilateral throat pain, while the other side is not obvious. 3. Trauma: If the wall of the throat is damaged by foreign objects such as fish spikes and bones, which results in edema of the mucous membrane wall and mucous membrane breakage on one side, the diagnosis can be confirmed by fiberoptic laryngoscopy. If there is a unilateral sore throat, swallowing pain, it is recommended that patients go to the hospital, under the guidance of the doctor for treatment, do not use drugs without authorization, so as not to cause adverse consequences.