Gastropathy is one of the most common diseases in clinic, and the law of development is generally mucosal injury → superficial gastritis → atrophic gastritis → intestinal epithelial hyperplasia → atypical hyperplasia → early gastric cancer → progressive gastric cancer. Firstly, it starts from the damage of gastric mucosa, which is prolonged and gradually develops into superficial gastritis. When the inflammation of gastritis extends to the deep part of glands, the glands are destroyed, the number of glands is reduced, the lamina propria is fibrotic, the folds of gastric mucosa disappear, and the gastric body and gastric sinus are atrophied, then it will be transformed into chronic atrophic gastritis slowly. Next, on the basis of chronic atrophic gastritis, long-term chronic inflammation makes the epithelial cells and glands in the mucosal layer gradually replaced by intestinal epithelial cells, and intestinal epithelial hyperplasia occurs. After intestinal epithelial hyperplasia, atypical hyperplasia will appear at the place of hyperplasia, which is mild at first, and then gradually turns into moderate and severe atypical hyperplasia, and on the basis of severe atypical hyperplasia, early gastric cancer, that is, carcinoma in situ, which invades the mucous layer and submucosa, and then invades further and develops into progressive gastric cancer. Therefore, if you have stomach discomfort, it is recommended to consult the doctor in time, complete gastroscopy and other examinations to clarify the gastric lesions, and then give appropriate treatments in time to avoid delaying the condition.