The treatment of vertebral artery hypoperfusion depends on what is causing it. If there is significant narrowing of the vertebral arteries within the skull or narrowing of the basilar arteries, the patient is usually advised to take antiplatelet medications such as aspirin, along with medications to improve microcirculation, like statins, to see if they can recirculate the brain, re-mediate, and be able to redistribute the blood flow from a new source. If there is severe stenosis below the opening of the vertebral artery or severe stenosis or occlusion of the subclavian artery, and the vertebral artery blood reflux causes insufficient blood supply, surgical intervention is needed. A medicated stent or conventional metallic stent can be placed in the opening of the vertebral artery, or even a medicated balloon dilatation without a stent can provide significant improvement. The subclavian artery can be stented with a coated stent or a conventional stent, which is very effective and has a very high long-term effect and patency rate. Depending on the specific cause of vertebral artery insufficiency, it is important to consider which treatment to use.