Stomach-enhancing and anti-inflammatory granules and omeprazole can be taken at the same time, it is recommended to follow the doctor’s instructions for medication. It has the efficacy of harmonizing the stomach and strengthening the spleen, activating blood circulation and regulating qi, and is used for epigastric pain, distension and poor feeding caused by spleen and stomach disharmony, and chronic gastritis with the above symptoms. Adverse reactions are not clear; it is not suitable for people with cold spleen and stomach, cold and dampness obstruction; it is forbidden for people who are allergic to this product and pregnant women. Omeprazole can inhibit gastric acid secretion, treatment of duodenal ulcer, gastric ulcer, reflux esophagitis, stress ulcer. Adverse reactions can be seen diarrhea, nausea, gastrointestinal flatulence, headache, abdominal pain, constipation, etc.; severe renal insufficiency, allergic to the product, infants and young children are prohibited. The instruction manual of the gastric anti-inflammatory granules and omeprazole does not clearly indicate that the two will occur drug-drug interactions, there is no contraindication, so they can be taken together, and it is recommended that they be used under the guidance of a doctor.