Is free psa/total psa 19.59 serious?



Free PSA/total PSA19.59 is mostly a normal manifestation with relatively low severity, which needs to be considered in combination with serum PSA and other tests.

PSA is a prostate-specific antigen, which is secreted by the prostate gland and exists in the epithelial cells of the prostate ducts, and can be significantly elevated in prostate cancer.

Under normal circumstances, the body’s free PSA/total PSA value should be greater than 0.25, of which free PSA should be less than 0.8 μg/L and total PSA should be less than 4 μg/L. If the ratio decreases and is accompanied by an elevation of both free PSA and total PSA, it is usually indicative of the presence of prostate cancer.

Therefore, a free PSA/total PSA of 19.59 with both free and total PSA within the normal range is normal. If prostate disease is suspected, CT, MRI and pathology are often needed to confirm the diagnosis. It is recommended to seek timely medical treatment and standardized diagnosis and treatment if necessary.