Colorectal cancer is one of the common malignant tumors in humans. Early diagnosis is the key to improve the prognosis of colorectal cancer patients, and standardized surgery and comprehensive treatment for patients with progressive and advanced tumors can also improve the treatment outcome. Based on the lymph node metastasis pattern of colon cancer and the theory of complete mesenteric resection, the surgical treatment of colon cancer has entered the era of standardization and standardization. Based on the gold standard of total mesorectal excision (TME), the surgical approach for rectal cancer, especially low rectal cancer, needs to be individualized. Although colorectal cancer liver metastasis is an advanced disease, research on its treatment is very active. For resectable colorectal cancer liver metastasis tumor, liver resection is the standard treatment and the only possible radical treatment. Therefore, it is particularly important to determine the resectability of colorectal cancer liver metastases. Surgeons are the most important participants in the clinical practice of colorectal cancer diagnosis and treatment, and standardized diagnosis and treatment are the key to improving patient prognosis.