The typical clinical manifestation is divided into three phases, including the chill phase, in which the patient feels cold, followed by generalized muscle chills, pale skin and bumps, which lasts for about 15-60 minutes, and then enters the fever phase, in which the patient has a generalized fever, red face and body temperature can rise to 40℃ or even This period lasts for about 2-6 hours and is accompanied by headache, body aches, nausea and other symptoms. During the sweating period, the patient sweats profusely and the body temperature drops rapidly, even lower than normal, and the patient feels weak and drowsy, which lasts about 2-4 hours. Therefore, the total duration of an attack of Plasmodium vivax is about 6-10 hours. During the interval of the attack, the patient has no discomfort and the body temperature is normal.