The pain on both sides of the perineum may be caused by improper sexual life style, local inflammation, genital herpes, etc. It can be treated by massage and hot compresses, topical application of fusidic acid cream, oral acyclovir and so on. 1. Improper sex life: due to incorrect sex life position or too much force in sex life, it is easy to cause redness, swelling and pain on both sides of the perineum. The symptoms can be relieved by abdominal massage and hot compresses, and in serious cases, potassium permanganate solution can be used for sitz baths. 2. Local inflammation: If you suffer from vulvitis, folliculitis and other local inflammation, it will also lead to redness, swelling, pain and itching on both sides of the perineum. It can be treated by topical application of fusidic acid cream, mupirocin cream and other drugs. 3. Genital herpes: Herpes is caused by herpes virus infection in the genitals, and some small blisters will grow in the perineum, resulting in redness, swelling and pain on both sides of the perineum. It can be treated by taking medicines such as acyclovir and vasiclovir. There may be other reasons for the pain on both sides of the perineum, when patients with pain symptoms on both sides of the perineum, need to go to the hospital in time, the specific use of drugs under the guidance of the doctor for standardized treatment.