The contraindications of Zhu Sha An Shen Pill include avoiding spicy and stimulating food during the period of taking the medicine, and avoiding those with insufficient heart qi and indigestion. It is not suitable for long-term use. Zhu Sha An Shen Pill is a commonly used Chinese medicine, the main ingredients of which are Zhu Sha, Angelica sinensis, Coptis chinensis and other Chinese herbs, which has the effect of calming the mind (using drugs of heavy nature to stabilize the mind), nourishing blood and benefiting the qi. It is mainly used in the treatment of insomnia and dreaminess, palpitations (rapid heartbeat, often accompanied by panic) and other symptoms. In addition to the above contraindications, the cinnabar in this drug should not be taken more often or for a longer period of time to avoid causing mercury poisoning. Secondly, it is contraindicated for younger children and pregnant women to avoid affecting the growth and development of children and embryos. Meanwhile, avoid taking the drug with iodide and bromide to avoid causing serious enteritis. It is recommended that patients with the above symptoms of insomnia and nightmares should first seek medical advice and choose the appropriate medication under the doctor’s diagnosis and treatment to avoid unauthorized use of medication and adverse consequences.