Proptosis is an important symptom in patients with hyperthyroidism. Proptosis is divided into simple proptosis and infiltrative proptosis. Infiltrative proptosis is also called malignant proptosis. Clinical manifestations of infiltrative proptosis include the following: 1. Protrusion of the eyeball is obvious, which can exceed 2mm, widening of the eye fissure and reduction of transient vision, etc. 2. Symptoms of soft tissue involvement around the eye, such as tearing, photophobia, foreign body sensation in the eye, eyelid swelling and hypertrophy, conjunctival congestion and edema, etc. 3. Involvement of the eye muscle. Long-term inflammation of the eye muscle can cause fibrosis of the eye muscle, resulting in The eye muscle may become fibrotic, resulting in a decrease or loss of eye movement, which may lead to limited eye movement or, in severe cases, eye fixation.4. Corneal involvement, long-term exposure of the cornea may lead to corneal ulceration, dryness, and concurrent bacterial infection, which may lead to corneal perforation and necrosis in severe cases.5. Involvement of the optic nerve, resulting in optic nerve papillary edema, optic neuritis, and, in severe cases, optic nerve atrophy and even blindness.