The patient’s eyes are swollen in the morning after waking up, which may be caused by drinking a lot of water or crying before going to bed, and may also be related to eye allergy or systemic diseases such as abnormal kidney function or hypothyroidism. 1. Physiological factors: If the patient drinks a lot of water before going to bed or cries for a long time, the swelling of the eyelids may appear in the morning, usually does not need special treatment, and can be relieved after rest. 2. Eye allergy: if the patient is allergic to pillowcase, quilt cover, etc., and develops allergic conjunctivitis and other eye allergic reactions, the patient may develop eyelid swelling, which may be accompanied by itchy eyes and other uncomfortable symptoms. 3. Kidney disease: patients with acute glomerulonephritis, nephrotic syndrome and other kidney diseases, because of water retention, patients may appear in the morning eyelids and facial and lower extremity edema, but also hematuria, proteinuria and hypertension. 4. Hypothyroidism: Hypothyroidism patients due to hypothyroidism or thyroid hormone resistance can cause generalized low metabolism performance, can appear pale, eyelid and facial edema, dull expression and other manifestations. It is recommended that patients with significant eye edema should seek prompt medical attention to evaluate their condition and follow the doctor’s instructions for treatment.