Menopause in a 46-year-old woman is usually a normal physiological phenomenon, but the possibility of pregnancy cannot be ruled out, and it may also be caused by polycystic ovary syndrome, ovarian tumors and other diseases. 1. Physiological phenomenon: with age, the function of the ovaries will gradually decrease until failure, menstruation stops. The age of menopause is usually between 45 and 55 years old, so menopause in a 46-year-old woman may be a normal physiological phenomenon. 2. Pregnancy: For women who usually have normal and regular menstruation and a history of sexual intercourse, the possibility of pregnancy cannot be ruled out, which is usually accompanied by nausea, vomiting, drowsiness and other early pregnancy reactions, and pregnancy can be ruled out through early pregnancy test or blood test for chorionic gonadotropin. 3. Polycystic Ovary Syndrome (PCOS): This is a common reproductive endocrine metabolic disease, which is characterized by menstrual disorders in the early stage, including scanty menstruation, scanty menstruation or amenorrhea, and may be accompanied by hirsutism, acne, and loss of female secondary sexual characteristics, such as smaller breasts and enlarged clitoris, and so on. 4. Ovarian tumor: As ovary is located in the deep pelvis, patients may not have obvious symptoms in early stage, with the progress of the disease, patients may have symptoms such as abdominal distension, abdominal pain, abdominal mass and so on. Functional ovarian tumors can have too much androgen, which can cause menstrual disorders, manifested as menopause, delayed menstruation, etc. Some patients can also have postmenopausal vaginal bleeding. The 46-year-old woman stops menstruation, after excluding physiological factors, should consult the doctor in time to find out the cause, and if necessary, carry out targeted treatment.