Gastrin 17 (G-17), also known as small gastrin, is one of the most important hormones secreted by gastric sinus cells, and its role is to stimulate gastric acid secretion and stimulate gastrointestinal motility. Gastrin 17 can be measured clinically through a blood test. The normal range of gastrin 17 should be 1-15 ng/L, with a certain range up and down, and the test of gastrin 17 can initially determine a variety of diseases, which has a greater clinical significance. When gastrin 17 is abnormal, it indicates that the patient may have abnormal gastric acid secretion, indicating that the patient may have gastrointestinal pathologies, such as atrophic gastritis, Helicobacter pylori gastritis, hypergastrinemia, gastroesophageal reflux, gastric ulcer, gastrinoma, gastric cancer and other diseases. In addition, some systemic diseases such as short bowel syndrome and hyperthyroidism can also cause an increase in gastrin 17. It is important to note that gastrin 17 is a diagnostic test that can only be used as an aid to diagnosis, and that gastrin 17 alone cannot detect disease. If the patient also needs to undergo gastrin 17 test, it is recommended that the patient should try to avoid food before the test so that the food in the stomach does not affect the test value, and should actively cooperate with the doctor during the test and carry out targeted treatment after the diagnosis of comprehensive test results.