LDL 4.16mmol/L should be combined with cerebrovascular risk factors to assess the degree of risk. Patients with a combination of multiple risk factors (e.g., hyperlipidemia, hypertension, diabetes mellitus, etc.) have relatively severe conditions. LDL 4.16 mmol/L exceeds the normal value, and the upper limit of normal LDL is 3.37 mmol/L. Patients with elevated LDL should be evaluated for severity in combination with risk factors, and common risk factors include smoking, diabetes mellitus, a history of early-onset cardiovascular and cerebrovascular disease, hypertension, and hyperlipidemia. For patients without risk factors, the risk of slightly elevated LDL is relatively low and generally does not require oral medication, but a strict dietary restriction should be imposed to avoid high-fat foods, and regular testing of LDL should be performed. Patients with multiple cardiovascular and cerebrovascular risk factors are at high risk for cardiovascular and cerebrovascular disease, and their condition is relatively serious, so they need to be treated with oral statins, such as atorvastatin, as prescribed by the doctor. Other risk factors should also be attended to and treated. The main effect of atorvastatin is to inhibit cholesterol synthesis, and it can be used for the treatment of patients with elevated LDL. Adverse effects of the drug include diarrhea, joint pain, nausea, nasopharyngitis, gastrointestinal flatulence, and abnormalities of liver function, etc. It is contraindicated in patients with allergy to the drug components, unexplained liver enzyme elevation, and in women who are pregnant and breastfeeding. Patients with elevated LDL should seek medical attention in a timely manner, and actively diagnose and treat under the guidance of a physician to avoid adverse consequences.