Babies always have frequent coughs that do not work well with medication. They need to be analyzed for etiology and given targeted treatment according to the cause. 1. Drug-resistant bacterial infections, many bacterial or mycoplasma infections are not effective due to antibiotic resistance, causing coughing to become more and more serious. The cough is mainly at night and in the early morning. The child needs to be checked for allergens to avoid contact with allergens and to have an exhaled breath nitric oxide test and pulmonary function test, and if there are abnormalities, longer-term treatment may be required, with monthly assessment to adjust the medication. 4. Upper airway syndrome, due to nasal reflux irritating the pharynx can also cause recurrent bad cough in children. Therefore, if a long-term cough does not heal, there must be triggering factors, and the triggering factors must be identified to better treat the disease in the child.