The medications that may be involved in the treatment of bad breath are antibiotics, NSAIDs, and gargles, and there are cases where no medication is needed. Halitosis should be treated with medication based on a clear understanding of the cause, and it is recommended that the cause be addressed and treated. There are many causes of bad breath, such as periodontitis, gingivitis, diabetic ketoacidosis, etc. The treatment and medication are different for different causes. If the bad breath is caused by gingivitis, periodontitis, you can use antibiotics as prescribed by the doctor, such as local use of minocycline gel, chlorhexidine acetate solution, etc., or the use of metronidazole, amoxicillin, erythromycin and other systemic medication. For those who experience painful symptoms, non-steroidal anti-inflammatory drugs such as ibuprofen and acetaminophen are also used to relieve pain. However, conventional periodontal therapy is the most effective method, and medications only play a supporting role. If the bad breath is caused by diabetic ketoacidosis, active treatment of the primary disease is needed. Commonly used medications include insulin, sodium bicarbonate, dextrose, potassium chloride, etc., in order to lower blood glucose, correct electrolytes and acid-base balance. In addition, if the bad breath is caused by diet, bad habits and other physiological factors, there is no need to use drugs, pay attention to brushing teeth, gargling and so on. It should be noted that the above drugs need to be used under the guidance of a doctor, not blindly used on their own.