Down refers to Down’s syndrome and 21 refers to trisomy 21. High risk of trisomy 21 from Down’s syndrome requires a decision on whether the pregnancy can continue based on the results of non-invasive DNA testing and amniocentesis.
Down’s screening is done by taking the blood of a pregnant woman and checking her alpha-fetoprotein, chorionic gonadotropin, free estriol, etc. It is then used in conjunction with the woman’s age, weight, and week of gestation to determine the level of risk for the fetus to have trisomy 21.
Whether a fetus with high risk of trisomy 21 from Down’s syndrome screening can be wanted or not needs to be judged based on the results of the test in a comprehensive manner. If the non-invasive DNA test results are normal, the pregnancy can continue. If the non-invasive DNA test results are abnormal, amniocentesis is required. If the test results are normal, the pregnancy can continue, but if the test results are abnormal, the pregnancy needs to be terminated.
In conclusion, after checking out the high risk of Down’s syndrome, it is recommended to consult a doctor in time, after the doctor’s interview to carry out other related projects, amniocentesis is the gold standard for determining whether there is chromosomal abnormality in the fetus, if the amniocentesis suggests that there is trisomy 21 in the fetus, it is more likely to need to terminate the pregnancy in a timely manner.