Appendicitis occurs when the right lower abdominal pain is not serious, may be a manifestation of chronic appendicitis, or local inflammation is relatively mild. After the onset of chronic appendicitis, the symptoms of lower right abdominal pain may not be serious, but the course of the disease is relatively long, and there may be recurrent episodes of abdominal pain. Appendicitis in the early stage of the onset of the local intestinal mucosal tissue of the inflammatory response will be mild, there will be a lower right abdominal pain is not serious performance, or even the early appearance of the epigastric or periumbilical pain, and later transferred to the lower right abdomen. There is a possibility that the patient neglected and delayed the best time for treatment. In addition, when the appendix is purulent, edema is serious, resulting in severe pain in the affected area. When there is pus and perforation, the internal pressure of the appendix is significantly reduced, and temporary pain relief can occur. Appendicitis patients do not always have severe abdominal pain symptoms, sometimes the right lower abdominal pain may not be serious, it is best to recommend abdominal ultrasound, CT and blood tests and other ancillary tests, diagnosis is recommended timely surgical treatment, and intravenous use of ceftriaxone sodium, levofloxacin and other antibiotic treatment.