The success rate of bone marrow transplantation for remittance is mainly related to the chance of bone marrow mating. If the bone marrow donor is a perfect match, the success rate of bone marrow transplantation is more than 90%, and if it is a semi-matched bone marrow donor, the success rate of transplantation is around 50%.
1. The success rate of bone marrow transplantation is higher, above 90%, when performed by a fully compatible donor, and the probability of postoperative immune rejection is greatly reduced.
2. The probability of graft failure and immune rejection after bone marrow transplantation increases with half-matched ligands, and the graft success rate is around 50%.
However, it is very difficult to find a perfectly compatible ligand. The chance of bone marrow mating is 100% between identical twins, 50% between parent-children, only about 25% between biological siblings, and lower among other relatives. In addition the probability of finding a fully compatible donor between unrelated bone marrow matches is particularly small, at about 1 in 200,000
Therefore, patients undergoing bone marrow transplantation for remodeling should actively follow their doctor’s instructions and remain optimistic at the same time.