Kidney disease refers to the morphology of the kidney, or problems with its function, are kidney disease. The kidney itself is a normal parenchymal structure, if a cystic structure appears, a renal cyst appears, this is its morphological alteration. There are also changes in size and thickness, such as some special congenital genetic diseases with thin cortex; or the size of both kidneys should be normal is about 9-11cm, and then some kidneys become smaller, this is the morphological problems of kidney disease. There is also a problem with his function, the function of the kidneys is to concentrate urine, urine, toxins, as well as the function of drainage of water. Generally, the kidney function test is to check creatinine and urea nitrogen in blood biochemistry, or urine test to check whether there is hematuria and proteinuria. If there is a problem with urine routine or kidney function, it may be necessary to do a kidney puncture biopsy or glomerular filtration rate measurement, which are some means to check kidney disease.