A normal blood count does not reveal the presence of thalassemia. Thalassemia is a small-cell hypochromic anemia caused by the disorder of synthesis of hematopoietic raw material bead protein, which is a hereditary disease and mainly manifests as the manifestation of hemolytic anemia. 1. The blood routine of thalassemia patients is usually microcytic hypochromic anemia, which is manifested by the decrease of the average volume of red blood cells, the decrease of the average hemoglobin volume of red blood cells, and the decrease of the average hemoglobin concentration of red blood cells, and the more serious the condition is, the more obvious the decrease of these indexes is. Therefore, if the patients have microcytic hypochromic anemia, the possibility of thalassemia can be considered, but the diagnosis of thalassemia is not made. 2. In patients with thalassemia minor or thalassemia quiescent, the blood routine indexes can be normal, so the normal blood routine can not be excluded from thalassemia. Thalassemia needs to be diagnosed by hemoglobin electrophoresis and genetic testing. When abnormal blood counts occur, it is recommended to consult a doctor in time, complete the examination and identify the cause of the disease, and then give targeted treatment or therapy under the guidance of the doctor.