Left heart enlargement is the result of the body compensating for impaired left heart function and is generally irreversible. There are some cutting-edge drugs used to reverse heart enlargement, but their effect is very weak. Left heart enlargement is caused by congenital diseases (such as dilated heart disease, hypertrophic heart disease, etc.) or acquired heart diseases (such as hypertensive heart disease, coronary heart disease, etc.), and it is a fundamental process in the development of heart failure. Once enlargement of the heart is detected, it proves the presence of cardiac insufficiency, a process that cannot be reversed, and therefore the enlarged left heart usually cannot be recovered. Although the enlargement of the left heart is irreversible, its continued enlargement can be delayed by medications such as aldosterone receptor inhibitors such as spironolactone and angiotensin receptor inhibitors such as valsartan, which have the effect of delaying ventricular remodeling, and can be applied under the guidance of a physician.