Running pain in the middle tendon of the sole of the foot is considered plantar fasciitis or muscle strain. 1. Plantar Fasciitis: Frequent running causes an increase in the load on the plantar muscles and fascia, and aseptic inflammation occurs at the stopping point of the plantar fascia when it is repeatedly pulled, resulting in pain. It is usually unilateral and can be alleviated after rest. You can wear orthopedic insoles, shock wave physiotherapy, ultrasound physiotherapy. The effect of conservative treatment is not good, you can take closed injection. 2. Muscle strain: consider too much exercise or exercise before not enough warm-up caused by localized swelling, pressure and pain, you can take ice packs, under the guidance of the doctor external diclofenac diethylstilbestrol cream, oral nimesulide dispersible tablets. If the pain in the middle tendon of the sole of the foot is not improved by resting, you need to consult a doctor in time.