Acute sinusitis in children, which can be secondary to acute rhinitis, antibiotic treatment usually requires the use of 1 to 2 weeks, should be based on the specific circumstances. Treatment with antibiotics should choose antibiotics that are sensitive to the pathogenic bacteria, and the antibiotics that can be used are penicillin, cefixime, azithromycin and so on. Symptoms can mostly be effectively controlled after 1~2 weeks of antibiotic use, but special cases cannot be ruled out. Anaerobic infections require concomitant use of tinidazole and metronidazole. If symptoms worsen after 48-72 hours of antibiotic treatment, or if there is no improvement in symptoms for 3-5 days, alternative treatment should be carried out in time to re-evaluate the sensitive pathogens. It is recommended to consult a doctor and follow the doctor’s instructions to avoid the development of acute sinusitis into chronic sinusitis.