It is important to pay attention to and be aware of the fact that waking up with breath-holding during sleep can be caused by sleep apnea hypopnea syndrome or coronary artery disease or heart failure in cardiovascular diseases. Sleep apnea is one of the most common conditions. Chest tightness, breath-holding or sudden awakening from sleep are mostly seen as clinical symptoms caused by these disorders. Sleep apnea hypoventilation syndrome patients are characterized by obesity is more obvious, especially the emergence of the neck short, thick, snoring phenomenon is more serious during sleep, and even apnea, pause in the apnea state, the patient will be suffocated to wake up. This kind of disease belongs to the more important risk factors of cardiovascular and cerebrovascular diseases, but also easy to lead to the occurrence of sudden death, you can improve the sleep monitoring in the hospital respiratory department or sleep medicine department, to confirm the diagnosis. Treatment can be improved by wearing a ventilator or surgical treatment. Some belong to the cardiovascular disease caused by sleep suffocation, such as coronary heart disease patients at night myocardial ischemia, heart failure patients with pulmonary stasis obvious, paroxysmal nocturnal dyspnea.