Bone marrow aspiration needs to pay attention to preoperative communication, intraoperative operation standardization, postoperative sterilization and pain relief. 1. Preoperative communication: Before the operation, we need to explain the significance of bone marrow aspiration to the patients, get the patients’ understanding, briefly introduce the operation steps, so that the patients can be well prepared psychologically and reduce the tension. 2. Intraoperative operation standardization: pay attention to good disinfection when performing bone puncture, try to be gentle to avoid side injuries, the patient should cooperate with the physician as much as possible in this process, and change the appropriate body position. 3. Postoperative disinfection and pain relief: After bone puncture, change the medicine and disinfection at regular intervals. Since bone puncture often causes severe pain, painkillers such as buclizine hydrochloride injection should be used in time to relieve the symptoms. All of the above drugs should be used under the guidance of physicians, avoid self-medication.