Whether grade III invasive ductal carcinoma of the breast can be cured or not depends on many factors such as the patient’s age, physical fitness, the stage of the disease and the treatment method. Invasive ductal carcinoma of the breast is a type of breast cancer, grade III is the way of grading in histology, grade III belongs to low differentiated tumors and highly malignant tumors, which are more difficult to treat and have higher recurrence and metastasis rates compared with grade I and grade II. The treatment of invasive ductal carcinoma of the breast is a comprehensive treatment mainly based on surgery. The prognosis is related to the clinical stage, the 5-year survival rate of patients with stage I breast cancer is 90%-95%, stage II is 70%-80%, stage III is 25%, and stage IV is about 10%, and if there is no recurrence after 5 years, it generally indicates that clinical cure has been achieved. Therefore, whether grade III invasive ductal carcinoma of breast can be cured or not depends on whether the patient has recurrence after treatment. It is suggested that patients should go to regular hospitals for consultation in time and receive treatment according to medical advice.