Whether to continue vaccination after three doses of rabies vaccine should be decided according to whether it is pre-exposure prophylaxis or post-exposure prophylaxis, as follows: 1. Pre-exposure prophylaxis: no vaccination is required after three doses of rabies vaccine. Pre-exposure prophylaxis usually refers to high-risk groups who have not been bitten or scratched by animals but have a high probability of having close contact with animals, including veterinarians, rabies researchers, etc. Usually, three doses of rabies vaccine are required, which should be completed on days 0, 7, and 28, respectively. 2. Post-exposure prophylaxis: It is not acceptable to have only three doses of rabies vaccine; four or five doses are required. Post-exposure prophylaxis should be carried out in time after being bitten by dogs, or bitten or scratched by other animals. Five vaccinations are usually required, completed on days 0, 3, 7, 14, and 28. Some vaccines apply a 2-1-1 vaccination program, with four shots completed on days 0, 7, and 21, two shots on day 0, and one shot in each of the right and left arms. When vaccinating with rabies vaccine, it is recommended to actively cooperate with the doctor’s guidance to complete the whole vaccination to avoid the occurrence of adverse reactions.