During the period of quadruple therapy, dietary precautions: avoid spicy stimulation, harder, greasier, and too cold food. Quadruple therapy is suitable for patients with Helicobacter pylori infection, such patients are usually accompanied by abdominal discomfort, so more attention should be paid to diet during the medication. During the treatment period, avoid spicy and stimulating food, which will cause abdominal distension and discomfort; do not eat nuts and other hard food, so as to avoid heartburn and other symptoms; do not eat greasy food, such as fat meat, which will cause abdominal distension, nausea and other symptoms; do not eat too cold food, such as cold drinks, which will lead to diarrhea and other symptoms. The same disease, the patient’s physical condition is different, different stages of the disease, the treatment method is different, should be standardized under the guidance of the doctor.