Hydrogen peroxide refers to a hydrogen peroxide solution, and shingles can be rinsed with a medical hydrogen peroxide solution, but it is not very useful in treating shingles. Herpes zoster is caused by a virus, and hydrogen peroxide solution is generally not used unless there is a secondary bacterial infection in the lesion. Hydrogen peroxide solution is often used to disinfect bacteria and is somewhat corrosive, so rinsing may cause some irritation and burning sensation to the affected area, and when used incorrectly it may aggravate the skin breakdown in the affected area and worsen the infection. When a patient develops shingles, he or she may choose a type of topical medication that is antiviral, prevents infection, or relieves pain. Examples include topical acyclovir cream or penciclovir cream. In the absence of herpes zoster breakouts, topical glycerite lotion can be used. After herpes breakout, 3% boric acid solution or 1:5000 furacilin solution can be used to apply wet compresses to the affected area. It can also be combined with ointment to prevent local infection, such as 0.5% neomycin ointment or 2% mupirocin ointment. And for herpes zoster that causes significant nerve pain, compound lidocaine ointment can be used topically to relieve the pain. When shingles is present, medical hydrogen peroxide can be used to disinfect the area. However, it still needs to be used in conjunction with other medications, and patients should seek medical attention and follow the doctor’s instructions for medication.