The generic name of Nifedipine Extended-Release Tablets (II) and Amlodipine Tablets (mostly referred to as Amlodipine Benzenesulfonic Acid Tablets) can both lower blood pressure and belong to the same class of antihypertensive drugs, with comparable therapeutic effects, which vary from person to person, and it is impossible to judge who is better. 1. Nifedipine extended-release tablets (II) can treat hypertension, angina pectoris, should be prohibited in allergic to the product, pregnant women and children, used with caution in liver and kidney insufficiency, low blood pressure, severe aortic valve stenosis. Adverse reactions such as lower limb edema, headache, chest pain, flushing, blurred vision, palpitations, decreased blood pressure, nausea, loss of appetite, abdominal pain, etc. may occur after use. 2. Amlodipine benzenesulfonate tablets can also be used to treat hypertension and angina pectoris. Adverse reactions are rare such as edema, itching, rash, nausea, abdominal pain, headache, insomnia, fatigue, muscle cramps, and flushing. It should be prohibited to use in patients who are allergic to dihydropyridine calcium antagonists. 3. The above two drugs are calcium antagonists, meet the indications for the use of drugs will obtain a certain efficacy, but the specific differences in individual, so that the efficacy of the use of the two drugs is not exactly the same, can not be compared to the overall efficacy of who is better to lower blood pressure, the specific use of the efficacy of the drug should be different from person to person. The use of specific drugs should be carried out under the guidance of specialists, not unauthorized use of drugs.