A high HCG value in Down’s syndrome screening indicates a high risk value and the possibility of Down’s syndrome in the fetus, but there are other reasons for a high HCG value. It is also possible that the HCG value is higher in twins than in singletons, and it is possible that an abnormal pregnancy, such as a gravida, may also cause a high HCG value. Therefore, there is no need to worry too much when the HCG value is high, and further non-invasive DNA or amniocentesis tests can be performed to confirm the diagnosis. During pregnancy, you should pay attention to diet and nutrition, pay attention to iron and calcium supplementation during pregnancy to prevent calcium deficiency from causing calf cramps and iron deficiency anemia, eat more fresh vegetables and fruits, and do all pregnancy tests regularly.