Immunohistochemistry is performed for breast papilloma, mainly based on the immunohistochemistry method to develop the next treatment plan. Tumor immunohistochemistry is one of the important reference indexes for the diagnosis and treatment of breast cancer, and this test is usually performed after the pathological examination. Performing immunohistochemistry is also helpful for the follow-up observation of breast papilloma in the future. In fact, immunohistochemistry is generally recommended for patients after tumor surgery. Based on the immunohistochemistry results, doctors can further determine the next step of treatment, such as whether radiation therapy is needed. However, the immunohistochemistry results are not absolute, doctors will combine with clinical symptoms, imaging tests and other comprehensive analysis, and then symptomatic treatment. Patients with papilloma should develop good living habits, especially pay attention to personal hygiene.