Newborn fever 38℃, whether the condition is serious needs to be analyzed comprehensively according to other conditions: 1, not serious: if the fever is only caused by acute upper respiratory tract infection, the mental state is relatively good, and there is only nasal congestion and runny nose. This condition is often caused by viral infections and is self-limiting, often within a week the condition will be significantly relieved; 2, serious: although the fever is 38 ℃, the body temperature is not particularly high, but the mental state is relatively poor, eating milk is not good, playing is not good, this condition is often due to serious infections, such as sepsis, septic meningitis and other serious diseases caused. The condition is serious and requires prompt treatment, such as the application of cephalosporin for anti-infection treatment. In case of convulsions, prompt anti-convulsive treatment is required.