Gallbladder wall roughness can generally be recovered in about two weeks, the specific recovery depends on individual physique and severity. Gallbladder wall roughness refers to the gallbladder wall is not smooth, localized thickening, belongs to a kind of imaging examination manifestation, mainly caused by physiological factors and pathological factors. 1. Pathological factors: it may be caused by cholecystitis, chronic nephritis or gallbladder stones, etc. It is necessary to go to the hospital in a timely manner and under the guidance of the doctor for symptomatic treatment, so as to control and improve the disease. 2. Physiological factors: it may be caused by irregular diet, long-term high-fat diet, which leads to roughness of the gallbladder wall. Usually pay attention to the dietary rules, diet to light, avoid too much spicy stimulation greasy food intake, if the symptoms are gradually serious, to go to the hospital in time for treatment, to avoid more serious symptoms.