The treatment of herpes zoster, also known as shingles, is focused on relieving pain in the acute phase, reducing the duration of the rash, preventing the spread of the rash, and preventing and reducing complications. Medication is divided into three main levels, including antiviral medication, pain medication, and reduction of related complications. Specific treatment begins with general management, such as wearing loose clothing to reduce friction, and using applications and lotions, such as glyburide lotion, to soothe and cool the skin. In addition, some antiviral drugs are needed for suppression, including acyclovir, valacyclovir, etc. Symptomatic management with pain medications such as NSAIDs, or tramadol, etc. is also possible. The use of further hormonal therapy is still controversial and depends on the patient’s symptoms and pain.