Artificial knee arthroplasty, an effective treatment for advanced knee lesions, is technically mature and can effectively relieve pain, improve function, correct deformity, and improve quality of life. Post-operative pain, swelling, quadriceps muscle weakness, reflex inhibition, and complications affect the efficacy of surgery and prolong the time to return to normal life. Rapid rehabilitation surgery technology can improve the pathophysiological changes of patients in the perioperative period, reduce surgical complications, shorten the recovery time of patients, and improve the effect of rehabilitation training through multiple channels, modes and means. The key to rapid rehabilitation surgery technology is to establish standardized procedures, including preoperative patient education and assessment, preoperative optimization of physical function, surgical technique improvement, perioperative blood and anticoagulation management, multimodal joint pain, perioperative rehabilitation program and exercise, and development of discharge criteria and other technical measures; at the same time, based on the characteristics of each patient, respectively, to develop a standardized, individualized and continuous comprehensive treatment plan In order to ensure medical safety, we have been able to achieve comprehensive management of the patient’s perioperative period, so that patients with total knee arthroplasty can obtain the best results, get out of bed within 48 hours after surgery, and discharge time is significantly shortened to 5 days. Case: Female, 74 years old, left knee osteoarthritis (degenerative arthritis, aging arthritis), cerebral infarction occurred 1 year ago, the right limb muscle strength was reduced, daily activities mainly relied on the left lower limb to support weight-bearing, and gradually developed severe pain in the left knee joint and difficulty in walking. Therefore, artificial total knee replacement of the left knee was performed, along with rapid rehabilitation surgical techniques. He was discharged from the hospital 5 days after surgery. 1.Preoperative X-ray frontal and lateral radiographs 2.Postoperative X-ray frontal and lateral radiographs 3.Knee extension and flexion within 24 hours after surgery Based on the improved surgical technique, extensive dressing and the use of blood drainage measures were no longer required after surgery. 4.Walking and turning on the ground within 48 hours after surgery 5.Walking and going up and down stairs at the review on the 14th postoperative day