Diabetic nephropathy edema usually appears in stage IV or V of diabetic nephropathy. The treatment plan is as follows: 1. Patients should strictly control the water intake, control the amount of water and water in food and strictly limit the salt intake; 2. Patients can be treated with diuretic drugs to reduce swelling under the guidance of doctors’ prescription. It is necessary to closely monitor electrolytes during the administration period to prevent electrolyte disorders, such as hypokalemia and hyponatremia. In the case of diabetic nephropathy, abnormal renal function is also prone to hyperkalemia. Therefore, if patients take diuretic drugs in the clinic, they need to closely monitor the electrolyte situation to prevent electrolyte disorders; 3, control blood sugar and blood pressure, glycosylated hemoglobin should be controlled below 7.5%; 4, high quality low protein diet, eat more lean meat and fish, avoid intake of vegetable protein such as soy; 5, if renal failure occurs, patients can be treated by hemodialysis, etc.