Sinus biopsy is not a test to check for H. pylori, but a test to diagnose the type of sinus lesion. H. pylori can be clearly diagnosed by carbon 13 urea breath test or carbon 14 urea breath test. Sinus biopsy will extract the mucosal tissue of the gastric sinus and observe the cellular morphology and glandular changes of the sinus through pathological sections, which can diagnose whether there is local cancer cell growth and clarify whether there is cancer. H. pylori needs to do carbon 13 urea breath test or carbon 14 breath test for clear diagnosis, usually a special liquid scintillation counter will be used, by measuring the breath count before and after the test, the ratio of the count can be calculated, greater than 3-5 times as positive, indicating the presence of H. pylori infection. H. pylori is an important causative factor for acute and chronic gastritis, peptic ulcers, and may even cause gastric cancer. H. pylori infection can cause gastrointestinal disorders, affecting digestion and absorption, and requires prompt treatment. In daily life, it is necessary to do a good job of preventing infection and to develop the habit of washing hands before and after meals.