Depression is very painful, some patients even pain, have the feeling that life is worse than death. Because: first, patients with depression often unexplained low mood, happy, no matter what kind of good things in the outside world, will not cause pleasant emotions. Second, because patients with depression often do not have self-confidence, low self-esteem, and even self-blame, self-sin, often think they can not do a good job, or can not achieve good results, and even blame themselves, think they are guilty, or even unforgivable. Third, because of the above reasons, patients may have thoughts of death or suicide, and some of them may also have suicidal behaviors. Fourth, because patients often have cognitive function, as well as the manifestation of psychomotor disorders, will affect the patient’s learning, work efficiency and social interaction, the patient’s self-esteem will be affected, there is no way to self-actualization, there is no way to realize the sense of self-worth.