Hand numbness and drooling may be caused by improper sleeping position, acute cerebrovascular disease, Guillain-Barré syndrome and other reasons. 1. Improper sleeping position: if sleep for a long time pressure on one side of the limbs and face, due to the obstruction of blood circulation, may be due to one side of the limb blood supply is not good numbness, as well as saliva is difficult to swallow, the phenomenon of drooling. 2. Acute cerebrovascular disease: acute cerebral infarction, cerebral hemorrhage patients, when the infarction site affects the sensory conduction, there will be numbness of the hands. Cerebral infarction can also cause paralysis of facial muscles or swallowing dysfunction, which can lead to drooling. 3. Guillain-Barré syndrome: patients with Guillain-Barré syndrome can have facial paralysis, numbness of the limbs, manifested as drooling and hand numbness. If the symptoms of hand numbness and drooling appear, you should go to the hospital in time, actively search for the cause of the disease, and follow the doctor’s instructions to standardize the treatment.