Commonly used, the safety factor of children’s antipyretic drugs are: 1, acetaminophen, oral absorption is rapid, complete, within 30 minutes can produce antipyretic effect, less gastrointestinal stimulation, platelets and coagulation function has no significant impact. 2, ibuprofen, antipyretic and analgesic effect is obvious, antipyretic stable and long-lasting, gastrointestinal stimulation is small. 3, antipyretic patches, no need to take orally, mainly through the skin evaporation to antipyretic, antipyretic effect Chinese patent medicine preparations, such as pediatric Chai Gui fever granules, pediatric antelope horn granules, pediatric clear heat Ning, etc., with little side effects, suitable for children with low fever.