The desire to vomit when hungry may be caused by physiological factors. The human body is in a state of hunger for a long time, blood sugar levels are relatively low, gastrointestinal function is weakened, prone to discomfort, which can be manifested as nausea and desire to vomit, which is a physiological manifestation of the body’s need to replenish energy, usually recovered after the supply of food. In addition, it may also be caused by disease factors, common diseases including peptic ulcer, chronic gastritis, functional gastrointestinal disease, etc. 1, peptic ulcer: easy abdominal pain when hungry, can also be manifested as hunger nausea, acid reflux, want to vomit. It is recommended that further gastroscopy be done to clarify the diagnosis, and acid-suppressing drugs, such as omeprazole, can be taken under the guidance of a doctor for treatment; 2. Chronic gastritis: most patients have no obvious symptoms, and some patients can have the performance of acid reflux, nausea and desire to vomit, which is more likely to occur because there is no food in the stomach to neutralize stomach acid when hungry. At this time should be under the guidance of a doctor, taking medication, and should pay attention to improve the daily diet; 3, functional gastrointestinal disease: functional gastrointestinal disease is a clinical syndrome caused by the interaction of biological, psychological and social factors, can have nausea, vomiting, diarrhea, constipation and other manifestations, the relationship with hunger can not be determined, but some patients in hunger, the above symptoms aggravated. This diagnosis can be considered if no organic lesion is found through all the auxiliary examinations and the above possibilities are excluded.