Vague pain in the right side of the upper abdomen is most commonly caused by cholecystitis and should be promptly examined by abdominal color ultrasound, mostly secondary to gallbladder contraction after overeating or after drinking alcohol; in addition, patients with gallbladder stones also have recurrent vague pain in the right side of the upper abdomen. During the attack period, oral anti-inflammatory drugs, broad-spectrum cefadroxil tablets, and anti-inflammatory and cholagogic tablets should be used. If the symptoms are not significantly relieved by conservative treatment methods, surgical treatment is required if necessary, that is, traditional open surgery or laparoscopic surgery to remove the gallbladder under anesthesia.